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1: Title: Deducing the mechanism of action of compounds identified in phenotypic screens by integrating their multiparametric profiles with a reference genetic screen.
Journal: Nature protocols (Nat Protoc), Vol. 9 (2): 474-90, 2014 .
Snippet: In our case, the query screen is the intracellular survival of mycobacteria and the reference is a genome-wide RNAi screen of endocytosis.
Affiliation: Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany. 1] Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), Dresden, Germany. [2] Faculty of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia. .
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