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1: Title: Integration of chemical and RNAi multiparametric profiles identifies triggers of intracellular mycobacterial killing.
Journal: Cell host & microbe (Cell Host Microbe), Vol. 13 (2): 129-42, 2013 .
Snippet: By integrating the multiparametric profiles of the chemicals with those of siRNAs from a genome-wide survey on endocytosis, we predicted and experimentally verified that two compounds modulate autophagy, whereas the third accelerates endosomal progression.
Affiliation: Max-Planck Institute of Molecular Cell Biology and Genetics, 108 Pfotenhauerstrasse, 01307 Dresden, Germany. .
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