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1: Title: SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking.
Authors: Kostaras, E, et.al. .
Journal: Oncogene, Vol. 32 (44): 5220-32, 2013 .
Snippet: Both gain- and loss-of-function perturbation of RNF11 and SARA levels result in delayed degradation of epidermal growth factor (EGF)-activated EGF receptor (EGFR), while loss-of-function sustained/enhanced EGF-induced ERK1/2 phosphorylation.
Affiliation: 1] Laboratory of Biological Chemistry, Medical School, University of Ioannina, Ioannina, Greece [2] Department of Biomedical Research, Foundation for Research and Technology-Hellas, Institute of Molecular Biology and Biotechnology, University Campus of Ioannina, Ioannina, Greece. .
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